Genes (TGFβ, CREBBP, LIMK1, GRIN3A, CACNA1A, NOTCH1, PPP3CA, WNT5A, LEF1, CAMK2, and MAP3K2) that were targets of these miRNAs (Table S14) appeared to be quite relevant in MDD pathophysiology [67–71]. Here, LEF1 is linked to major depressive disorder.