Epigenetic regulation of FKBP5 and its consequences on patient’s behaviour is well documented: accelerated age-related decreases in FKBP5 methylation are associated with childhood trauma and depressive phenotypes [63], whilst increased DNA methylation levels of FKBP5 have been found in patients suffering from post-traumatic stress disorders (PTSD) and major depressive syndromes [27]. The gene discussed is FKBP5; the disease is post-traumatic stress disorder.