Overall, these results indicate that DEPTH scores conform to the prognostic risk in breast cancer in that the luminal A&B subtype often has a better prognosis than the HER2-enriched and basal-like/TNBC subtypes and the basal-like/TNBC subtype has the worst prognosis among all breast cancer subtypes39. This evidence concerns the gene ERBB2 and breast carcinoma.