Importantly, huMG/macrophages from clusters C2, C3, and C8 expressed higher levels of the chemokine CD195 (CLL5), but comparable levels of IL-1β, IL-6, TNF, MIP-1β (CCL4), IL-10, and MCP-1 (CCL2) between MDD and control cases (Fig. 2e–g). Here, CCL2 is linked to major depressive disorder.