IL1B and major depressive disorder: Our results are in line with recent microarray-based transcriptomic profiling of cerebral cortex in 87 cases of MDD, revealing no significant changes (FDR-corrected P value > 0.05) in the gene expression of HLA-DR, TNF, IL6, IL1B, IL1A, IL3, IL5, IL8, IL10, ITGAM (CD11b), FKBP5, TLR2, CCL2, and CD14 compared with matched controls48.