TSPO and snowflake vitreoretinal degeneration: [11C]PK11195 is a ligand of the 18 kDa translocator protein (TSPO, or peripheral benzodiazepine receptor) and a well-established PET marker of microglial activation.5 Our overarching hypothesis was that neuroinflammation would be positively associated with SVD and that the degree of inflammation would relate to SVD severity.