Moreover, by analyzing DNA methylation in the genes commonly altered, it was evident that sporadic ALS patients were more similar to SOD1-related cases (12 altered genes in common), than sporadic ALS with C9orf72-related (1 gene in common), or SOD1 and C9orf72 (0 genes in common) cases. The gene discussed is C9orf72; the disease is amyotrophic lateral sclerosis.