KEGG (Kyoto Encyclopedia of Genes and Genomes) analyses indicated that these differentially expressed coding genes were enriched in signals such as ‘PI3K-Akt pathway, Focal adhesion, Transcriptional mis-regulation in cancers’, which was consistent with those most significantly activated signaling pathways in TNBC [27] (Fig. 1c). This evidence concerns the gene AKT1 and cancer.