INS and cyst: Since hyperinsulinemia induced by hyperandrogenism was associated with premature maturation and luteinization of granulosa cells, follicular growth arrest, anovulation and cyst formation [7, 8], results suggest that, by reducing testosterone level and probably insulin production by pancreatic β-cells, M. arboreus would have consequently reduced the hyperinsulinemic signal impairing ovarian dynamic, and would have restored it.