The proteomic profiling of CRC SW620 cell-derived exosomes showed the enrichment of metastatic factors (MET, S100A8, S100A9, and TNC), signal transduction molecules (EFNB2, JAG1, SRC, and TNIK), and lipid raft and lipid raft-associated components (CAV1, FLOT1, FLOT2, and PROM1) compared with the nonmetastatic primary cell line, SW480 [24]. Here, PROM1 is linked to colorectal carcinoma.