This genetic disorder is caused by de novo mutations of ARID1A (CSS2; 1p36.11; MIM 614607), ARID1B (CSS1; 6q25.3; MIM 135900), DPF2 (CSS7; 11q13.1; MIM 618027), SMARCA4 (CSS4; 19p13.2; MIM 614609), SMARCB1 (CSS3; 22q11.23; MIM 614608) or SMARCE1 (CSS5; 17q21.2; MIM 616938) genes. Here, SMARCB1 is linked to hereditary disease.