In 2019, it was found that partial loss of SMARCB1 function by monoallelic alterations was impossible to be covered with normal mRNA production from the intact allele, which leads to neurodevelopmental dysfunctions (including ACC), intellectual disability (exon 2) and choroid plexus hyperplasia (CPH) (exons 4 and 9). The gene discussed is SMARCB1; the disease is Intellectual disability.