Silica nanoparticles coated with [Ru(bpy)3]2+ bounded to the detection antibody have also been used in an immunoarray for different prostate cancer biomarkers (prostate specific antigen (PSA), prostate specific membrane antigen (PSMA) and platelet factor-4 (PF-4)) [70]. The gene discussed is KLK3; the disease is Familial prostate cancer.