IFNG and COVID-19: In a recent study, COVID-19 ICU patients suffered higher systemic inflammatory response due to increased plasma levels IL2, IL7, IL10, granulocyte colony-stimulating factor (GC-SF), interferon-gamma (IFN-γ)-inducible protein (IP10, CXCL10), MCP1, macrophage inflammatory protein 1 alpha (MIP1A), and TNF-α [79].