UHRF1 and Burkitt lymphoma: One CRISPR/Cas9 screen demonstrated that the ubiquitin ligase ubiquitin-like PHD and RING finger domain-containing protein 1 (UHRF1) and DNA methyltransferases (DNMT1 and DNMT3B) are necessary for the restriction of EBV latency III-associated oncoproteins in Burkitt lymphoma [32].