Furthermore, the expression levels of NF-κB (indicator of tumor cell proliferation, survival, and therapy resistance) was, by tendency, reduced due to the combinatorial treatment, while the expressions of caspase-8, c-caspase-8 and caspase-3 were not significantly affected in response to neither the combinatorial treatment or each of the either therapies alone. The gene discussed is CASP8; the disease is neoplasm.