,9 The complex methyltransferase-like 3 (METTL3)-Wilms’ tumor 1-associating protein (WTAP)- methyltransferase-like 14 (METTL14) is described as a miRNA adenosine methylase or writer, while FTO (fat mass and obesity-associated protein, UniProt: Q9C0B1) and ALKBH5 (alkylated DNA repair protein alkB homolog 5, UniProt: Q6P6C2) are described as miRNA adenosine demethylases or erasers.5 Here, ALKBH5 is linked to obesity due to melanocortin 4 receptor deficiency.