This was extended by Rabinovich et al.,59 who overexpressed citrin in a melanoma cell line and found that this increases aerobic glycolysis and invasiveness in an in vitro assay.f Both Alkan et al.58and Rabinovich et al.59notice that citrin is upregulated in some human tumors, but whether other MAS components were up was not checked. The gene discussed is SLC25A13; the disease is melanoma.