Larriba et al. [33] reported that colon cancer tissues that co-express Snai2 and Snai1 downregulated the vitamin D receptor, which mediates the antitumoral action of vitamin D. Sema3A is a ligand of neuropilin-1 and a tumor suppressor in acute leukemia [34]. This evidence concerns the gene SNAI1 and malignant colon neoplasm.