For the cardiac G×G, one SNP pair was identified through Biofilter modeling associated with venous thrombosis or pulmonary embolism: rs7735781 in XRCC4 and rs10804247 in XRCC5 (uncorrected LRT p = 3.20×10−6 and Bonferroni-adjusted LRT p = 0.0626996) (S4 Table). This evidence concerns the gene XRCC4 and pulmonary embolism.