In addition to BC, CLIC2 significantly downexpressed in 13 other cancer types, including bladder urothelial carcinoma, cholangiocarcinoma, COAD, kidney carcinoma, including kidney chromophobe and kidney renal papillary cell carcinoma, LIHC, lung cancer, including lung adenocarcinoma and LUSC, prostate adenocarcinoma, rectum adenocarcinoma, STAD, thyroid carcinoma, and uterine corpus endometrial carcinoma. The gene discussed is CLIC2; the disease is rectum adenocarcinoma.