Clearance of senescent cells whether genetically or pharmacologically has been shown to improve phenotypes in mouse models of Parkinson's disease (Chinta et al., 2018), tau‐dependent neurodegenerative diseases (Bussian et al., 2018; Musi et al., 2018; Zhang et al., 2019), and neuropsychiatric disorders (Ogrodnik, Zhu, et al., 2019). Here, MAPT is linked to neurodegenerative disease.