Accordingly, studies have shown that senescent cells increase in the brain during aging and neurodegenerative diseases (Jurk et al., 2012) and that removing senescent cells improves phenotypes in mouse models of PD (Chinta et al., 2018), AD, and tau‐dependent neurodegenerative diseases (Bussian et al., 2018; Musi et al., 2018; Zhang et al., 2019). This evidence concerns the gene MAPT and neurodegenerative disease.