For example, myxoid liposarcomas are characterized by reciprocal t(12;16)(q32;q16) translocation between the DDIT3(CHOP) and FUS genes, and synovial sarcomas demonstrate the translocation t(X;18)(p11.2;q11.2), which results in the fusion of the SS18 and SSX genes.16 A prospective, multicenter, French Sarcoma Group observational study demonstrated that diagnosis was modified after molecular genetics analysis for 53 (14%) of 384 patients with STS, and it has been argued that such testing should be considered mandatory.17 The gene discussed is DDIT3; the disease is synovial sarcoma.