The same benefit of RP was found among those with intermediate-risk PCa (HR = 3.42, 95% CI 2.00-5.84, p < 0.001), while no significant outcome was observed in GS = 7 [(HR = 2.52, 95% CI 0.61-10.47, p = 0.20) for GS = 3+4 and (HR = 1.33, 95% CI 0.30-5.83, p = 0.70) for GS = 4 + 3], indicating that the PSA level played a more important role than GS. Here, KLK3 is linked to posterior cortical atrophy.