EGFR and permanent neonatal diabetes mellitus-pancreatic and cerebellar agenesis syndrome: Despite disappointing clinical outcomes in PaCa patients treated with the parental CTX antibody, in spite of the nearly ubiquitous overexpression of EGFR in their cancers, our findings suggest that CTX may be repurposed as a highly effective, targeted delivery platform to courier cytotoxic drugs such as MMAE to PaCa cells.