CD8A and COVID-19: Overall, our data suggest that naïve A2/SARS-CoV-2−specific CD8+ T cells can indeed be expanded approximately fivefold and activated during the acute phase of COVID-19 but that, atypically for what we know for other readily resolved infections like influenza, both the extent of T cell proliferation and the persistence of activated T cells in the blood is low for (days 37 to 101 post disease onset) convalescent individuals.