HLA-DQB2 and cardiovascular disorder: We show some examples of PTWAS scan signals that seemingly violate the exclusion restriction in Fig. 8: GUCY1A1 to cardiovascular disease (CAD) in artery tibial (I2=0.94), CTB-171A8.1 to LDL cholesterol in artery aorta (I2=0.96), and HLA-DQB2 to height in muscle skeletal (I2=0.98) (the specific tissues are where the most significant PTWAS scan p values are identified).