TWIST1 and breast cancer: First, the GEPIA analysis showed that the expression levels of the epidermal marker CDH1 were upregulated in patients with BC compared to healthy individuals; in contrast, the mesenchymal marker (VIM) and the genes promoting the mesenchymal transition (SNAIL1/2, ZEB1/2, and TWIST1/2) were all downregulated in BC samples compared to the controls.