CD40LG and rheumatoid arthritis: In the inflammatory phase of rheumatoid arthritis, PBM improves the macrophages and lymphocytes activity, decreases the level of immune complexes, and regulates the level of immunoglobulins A (IgA), immunoglobulins M (IgM), immunoglobulins G (IgG), and the balance between pro-inflammatory and anti-inflammatory cytokines [195,196,197,198,199,200].