Epithelial tumor cells not only showed prolonged survival, but migrated significantly longer distances (350 μm compared with 150 μm, respectively, p < 0.01) and with greater velocity magnitude (4.5 μm/h compared with 2.1 μm/h, respectively, p < 0.001) under co-culture conditions and in response to exogenously administered FN. Here, FN1 is linked to neoplasm.