Herpesvirus infection pathway is mediated by numerous host and viral proteins which includes several pathways such as toll-like receptor signaling, pro-inflammatory cytokines, inhibition of apoptosis, antigen processing and presentation, JAK-STAT, calcium signaling, nuclear factor-kappa B (NF-κB), and B cell receptor signaling pathways [28,94,95]. The gene discussed is SOAT1; the disease is Herpesviridae infectious disease.