Dietary supplementation with lyophilized strawberries also exerts an anti-cancer effect against inflammation-mediated colon carcinogenesis in mice by reducing the expression of pro-inflammatory mediators, suppressing nitrosative stress, and decreasing phosphorylation of phosphatidylinositol 3-kinase, Akt, extracellular signal-regulated kinase and NF-κB [240]. The gene discussed is NFKB1; the disease is cancer.