DNM1L and brain ischemia: Moreover, Mdivi-1 was shown to abolish Drp1 dephosphorylation at Ser-637 in a rat model of cerebral ischemia [27], and to inhibit LPS-induced Drp1 phosphorylation at Ser-616, dephosphorylation at Ser-637, and translocation from the cytoplasm to mitochondria in a mouse model of sepsis [28].