DLEU1 is upregulated in several cancers, including non-small cell lung cancer [18], gastric cancer, clear cell renal cell carcinoma [19], glioma [20], bladder cancer [21], hepatocellular carcinoma [22], breast cancer [23], colorectal cancer [24], ovarian cancer [25] and cervical cancer [26]. Here, DLEU1 is linked to central nervous system cancer.