Deleted in lymphocytic leukemia 1 (DLEU1) is a lncRNA that is located on chromosome 13q14.3, and is aberrantly upregulated in several malignancies, including osteosarcoma, hepatocellular carcinoma, bladder cancer, glioma, cervical cancer, pancreatic ductal adenocarcinoma, colorectal cancer, non-small cell lung cancer, and oral gastric cancer [10]. The gene discussed is DLEU1; the disease is hepatocellular carcinoma.