In addition, the expression of MuRF1, MAFbx and FOXO3a, and autophagy markers such as ATG7 and LC3A/B, was increased, and AMPK/SKP2/CARM1 pathway activity was altered in CKD‐induced muscle atrophy and TNF‐α‐induced C2C12 cells. The gene discussed is FBXO32; the disease is chronic kidney disease.