SOX11 is amplified and overexpressed in ~30% of brain metastases in a recent study of a small cohort of breast cancer patients that were profiled using an integrated genomic and transcriptomic analysis of fresh frozen tumour samples (Saunus et al., 2017; Saunus et al., 2015) and highly expressed by ~30% of BCBM in another independent study (Varešlija et al., 2019). This evidence concerns the gene SOX11 and breast cancer.