Characterization of hMENA isoforms clearly showed that CAFs, as expected, were negative for the epithelial hMENA11a isoform (Fig 1A and Appendix Fig S2B and C) and for pan cytokeratin and E‐CADHERIN (Fig 1), which are expressed in cancer cells (Ep‐PDAC), and were immunostained by α‐SMA and Pan‐hMENA mAbs (the representative case PDAC#36 in Fig 1A). This evidence concerns the gene TBX1 and cancer.