Mechanistically, we identified that this hMENA‐mediated pro‐tumor function is attributable to its ability to regulate growth arrest‐specific 6 (GAS6) in CAFs and AXL in tumor cells, sustaining the pro‐tumoral paracrine GAS6‐AXL axis, described as crucial in EMT, drug resistance, and immune evasion (Gjerdrum et al, 2010; Jokela et al, 2018; Ludwig et al, 2018). The gene discussed is GAS6; the disease is neoplasm.