To investigate the role of hMENA in ligand‐dependent AXL signaling, we treated PANC‐1 cells with rGAS6 and we found that hMENA silencing inhibits GAS6‐mediated AXL and AKT phosphorylation (Fig 6D) and reduced cancer cell invasion toward GAS6 as detected by Matrigel transwell invasion assay (Fig 6E). Here, AXL is linked to cancer.