Conventional clinical screening and management of dyslipidemia with a traditional lipid profile may not be as sensitive to detail the overall atherogenic risk [37] and underestimate the severity of dyslipidemia in children and adolescents with T2D, detailed lipoprotein analysis including apo B measurements may be indicated in children and adolescents with T2D. This evidence concerns the gene APOB and type 2 diabetes mellitus.