Moreover, bevacizumab has been previously demonstrated to improve dexamethasone-refractory radiation-induced peritumor edema and necrosis.12,13 Therefore, the administration of bevacizumab may have inhibited the radiation-induced upregulation of VEGF, which led to a decrease in tumor size, improvement of the surrounding peritumor edema, and ultimately contributed to the improvement of the patient’s clinical status. Here, VEGFA is linked to neoplasm.