VEGFA and hemangioblastoma: They are commonly found below the tentorium, with 5% located in the brainstem.1 Hemangioblastomas are composed of stromal cells, which highly express vascular endothelial growth factor (VEGF), and are surrounded by a capillary network, composed of endothelial cells expressing VEGF receptor.1 We describe a case where bevacizumab, a humanized monoclonal antibody targeting VEGF, was successful in treating a surgical and stereotactic radiosurgical refractory hemangioblastoma.