Additionally, an enhanced expression of PRIM1 had a remarkable association with decreased OS in stage I-II HCC patients (HR = 1.86 (1.14-3.03), log-rank p = 0.012, Figure 5(b)) and stage II-III patients (HR = 1.93 (1.2-3.12), log-rank p = 0.0061, Figure 5(c)). This evidence concerns the gene PRIM1 and hepatocellular carcinoma.