AKT1 and alcohol drinking: The KEGG pathway analyses showed the upregulated genes were significantly enriched in 14 pathways including “ribosome”, “RNA transport”, “cell cycle”, “spliceosome”, and “alcoholism”, while the downregulated genes were significantly enriched in 25 pathways including “pathways in cancer”, “PI3K-Akt signaling pathway”, “human papillomavirus infection”, “MAPK signaling pathway”, and “focal adhesion”(Figures 5(g)–5(i)).