In addition, the results indicated that 9 of the 15 hub DEGs (FN1, SPARC, FBN1, BGN, UBE2C, SPP1, TIMP1, COL5A2, and CCNB1) in the PPI network were distributed in the three modules, suggesting that these genes may have important roles in GC. Here, COL5A2 is linked to gastric cancer.