In this study, we observed that sepsis led to cytokine storm accompanied by the upregulated serum levels of IFN-γ, IL-1β, IL-3, IL-4, IL-6, IL-10, IL-17, and TNF-α, whereas QX1 treatment decreased the production of typical Th1/Th2-associated proinflammatory cytokines (IFN-γ, IL-1β, IL-3, IL-6, and TNF-α) and Th17-associated proinflammatory cytokines (IL-17). The gene discussed is TNF; the disease is Sepsis.