Bioinformatics analysis revealed these DEGs were significantly associated with multiple biological processes, including myeloid cell apoptotic process, cellular extravasation, acute inflammatory response, neutrophil degranulation, macrophage activation, antimicrobial humoral response, collagen metabolic process, NF-kappa B signaling pathway, TNF signaling pathway, HIF-1 signaling pathway, Toll-like receptor signaling pathway, tuberculosis, legionellosis, complement and coagulation cascades, chemokine signaling pathway, circadian entrainment, ribosome, RNA transport, and spliceosome. The gene discussed is TNF; the disease is legionellosis.