This is also in line with a study suggesting that platelet-derived microparticles are able to transfer various receptors including CXCR4 to CXCR4-null cells and render them susceptible to HIV infection [30], thus triggering a number of physiological responses, some of which are proliferation of cells, adhesion, and chemotaxis, as well as inducing metastasis and angiogenesis in the lung and breast cancer [31, 32]. Here, CXCR4 is linked to HIV infectious disease.