We found that the iNOS-Iba1 colocalization and IL-1β-Iba1 colocalization in AD mice were decreased compared with those in the WT group (P < 0.01 in the PtA, Figures 6(e) and 6(g) and p < 0.05 in the Ent, Figures 6(f) and 6(h)). The gene discussed is NOS2; the disease is Alzheimer disease.