We observed that iNOS-Iba1 (P < 0.01 in the Ent, Figure 4(f)) and IL-1β-Iba1 (P < 0.01 in the PtA, P < 0.05 in the Ent, Figures 4(g) and 4(h)) colocalizations in AD mice were significantly increased compared with those in their age-matched WT counterparts. This evidence concerns the gene AIF1 and Alzheimer disease.