To further confirm that CD8+ T cells infiltrate into tumor tissues after combination therapy with anti-PD-L1 and LOXL2 inhibition or knockdown, we performed immunohistochemistry (IHC) stains for CD8 in primary and lung metastatic tumor tissues from the combinatorial treatment studies (Fig. 3a and Supplementary Fig. 5a). The gene discussed is CD8A; the disease is neoplasm.