While the extent of sarcopenia was lower in TA muscle than GAS or SOL (Fig. 2a), the expression of many genes involved in the muscle response to denervation (Chrng, Myog, Runx1, Chrna1, and Scn5a) was accentuated (>log2(1.5), Fig. 7e and Supplementary Fig. S9A–C). Here, SCN5A is linked to sarcopenia.