To date, nine disorders have been reported, including spinal and bulbar muscular atrophy (SBMA), Huntington’s disease (HD), several spinocerebellar ataxias (SCA1, SCA2, SCA3, SCA6, SCA7, and SCA17), and dentatorubral pallidoluysian atrophy (DRPLA)95. Here, CACNA1A is linked to Dentatorubral pallidoluysian atrophy.