In MR based on CAD data from 20,913 CAD cases and 95,407 controls, a null association of LIPG N396S with CAD was reported (6), with an OR for CAD of 0.99 (95% CI 0.88–1.11; P = 0.85) for the G allele encoding the missense mutation. The gene discussed is LIPG; the disease is coronary artery disorder.