In Cited1Cre;Fgf8f/+;Fgf17Δ/Δ;Fgf18f/Δ embryos, the omphalocele frequency was similar to that observed in TCre;Fgf8f/+;Fgf17Δ/Δ;Fgf18f/Δ embryos (Fig. 2G), suggesting the requirement for Fgf18 in VW closure is in the somites. Here, FGF18 is linked to omphalocele.