TARDBP and amyotrophic lateral sclerosis: Motor neuron-like NSC-34 cells were transfected with empty vector (encoding EGFP only) or either EGFP-tagged wildtype TDP-43, or ALS-associated mutants A315T or Q331K, and treated with either 13.5 μM etoposide or 100 μM H2O2 for 1 h, 24 h after transfection.